The effects of inhibition of fatty acid oxidation in suckling newborn rats.
نویسندگان
چکیده
Inhibition of fatty acid oxidation with pent-4-enoate in suckling newborn rats caused a fall in blood [glucose] and blood [ketone bodies] and inhibition of gluconeogenesis from lactate. Glucose utilization was not increased in newborn rats injected with pent-4-enoate. Active fatty acid oxidation appears to be essential to support gluconeogenesis and to maintain normal blood [glucose] in suckling newborn rats.
منابع مشابه
The effects of inhibition of gluconeogenesis in suckling newborn rats.
Inhibition of gluconeogenesis with 3-mercaptopicolinate in suckling newborn rats caused a fall in blood [glucose], but no change in their high plasma [free fatty acid] and blood [ketone bodies]. Active gluconeogenesis seems to be more important than sparing of glucose by high concentrations of fat-derived substrates for the maintenance of normal blood [glucose] in suckling newborn rats.
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ورودعنوان ژورنال:
- The Biochemical journal
دوره 166 3 شماره
صفحات -
تاریخ انتشار 1977